The story of the military unit organized by future U.S. President Teddy Roosevelt and its adventures in Cuba during the Spanish-American War of 1898. This film is lost.
Bella Donna ( Pauline Frederick ) a seductive woman snares Nigel Armine ( Thomas Holding ) into marriage and he takes her to Egypt to live. Tired of her simple husband, Bella becomes involved with brutish Baroudi. To get rid of Nigel, she begins slowly poisoning him. However, Nigel's friend Dr. Isaacson arrives in time to save him. Now Baroudi wants nothing to do with Bella, and neither does her husband. Totally alone now, the distraught Bella wanders off into the desert.
Wealthy American widow Elizabeth Carter plans to marry the Earl of Dettminster when lawyer Augustus Tucker informs her of a codicil in her late husband's will. The Carter fortune will go to nephew Pitney Carter, who is in love with Elizabeth, if her second husband is not an American. Elizabeth therefore pays penniless playwright Jasper Mallory $50,000 to marry her and schemes with actress Mme. Albani to provide grounds for divorce so that she may then make the earl her third husband.
Young Martha Redmond, a poor girl from a small town, leaves to find a singing career in New York City. She doesn't find success as a singer, but finds a job as a model for a prominent artist, and soon becomes his mistress. When her lover throws her over to marry the daughter of a wealthy man, she becomes a "fallen women", a plaything for wealthy playboys. She meets Barrett, a millionaire's son, and begins to wonder if she might have a future with him, but it seems like he'll turn out to be just like "all the others".
Miriam Monroe and John Conrad are two young scientific workers who, independently of each other, have discovered a chemical called exonite. Miriam discovered it while searching for a cure for cancer, while Conrad used it as a basis for a powerful explosive.
Overcome with guilt after having an affair with her best friends husband, Clorinda hopes to escape her past by moving to Europe, where she meets Malcolm, a decent man who falls in love with her.
Opera singer Renee Dupree is in love with struggling composer Julian who falls very seriously ill. She goes to impresario Mueller for the money Julian needs but is saved from sacrificing her virtue when a jealous lover kills Mueller.
Political graft collector, David Power forced by the district attorney to leave New York takes cabaret singer Hebe Norse with him. Showing talent in a variety of professions, Power is eventually hired by a great steel manufacturer, Gail Rogers. He falls in love with Rogers' daughter Rosalie, and they marry happily until Rogers returns home with a new wife…. Hebe Norse. When Rogers discovers Hebe's past, the two men sever ties as does Rosalie. Vengefully Rogers tries to ruin one of Power's companies without success. Ultimately Rosalie forgives Power and they and their young daughter are reunited.
Wealthy orphan Philippa L'Estrange loves handsome Norman Arleigh and is confident of marrying him until he discloses that he has only brotherly affection for her. Determined to have revenge, Philippa introduces Arleigh to Madeline Dornham and reveals on their wedding day that Madeline, his bride, is the daughter of the man who killed his mother. In the end it is learned that Madeline is Mrs. Dornham's daughter from a previous marriage, not the daughter of a criminal.
Impulsive flapper Elizabeth Winthrop, rebels against her parents and moves to New York after breaking with her fiance, Clayton Webster. Hugo Von Strohm, a wealthy playboy, procures Elizabeth a job as a chorus dancer and secretly pays her salary. After he tries to seduce her, Elizabeth sees through his kindnesses and returns to her parents and Clayton.
In Up and Going, based on Mix's own story, Arctic Trails, the star played a titled, polo playing Northwest Mounted Police officer. From an elderly woman, Tom learns that childhood girlfriend Jackie McNabb is being kept prisoner by evil Basil Du Bois.
In this detective picture, Janet marries Raoul Newell but leaves him when she finds out he is a thief. However, when he comes to her and asks her to help retrieve some papers stolen from him by Mr. and Mrs. Giles, she agrees and goes to work for the couple as a maid. But in reality, Raoul is after the couple's jewels.
Mary Alden and her brothers Matthew and George have extremely different political views. Matthew is a committed pacifist, and is constantly giving speeches against war. George is notified that his draft number, 258, has been called and to report for induction, but he refuses. Mary, on the other hand, is intensely patriotic and comes up with a plan to shame him into reporting for induction. Meanwhile, Matthew is being set up for a patsy by a gang of German secret agents, led by Van Bierman, who are planning to blow up an airplane factory.
Claire Martin, niece of the wealthy Mrs. Taylor, suffers from loss of memory. Under the effect of this, Claire acts as an entirely different person. She wanders through the woods seeking shelter and food, and finally reaches a cabin temporarily occupied by a New York sportsman, who is fishing and hunting in the woods.